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TargetCarbonic anhydrase 2
LigandBDBM10860
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1511555
Ki 170±n/a nM
Citation Vullo DDe Luca VDel Prete SCarginale VScozzafava ACapasso CSupuran CT Sulfonamide inhibition studies of theż-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. Bioorg Med Chem Lett 25:3550-5 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrase 2
Synonyms:CA-II | CA2 | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM10860
NameBDBM10860
Synonyms:4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 | MAFENIDE | aromatic sulfonamide compound 6 | aromatic/heteroaromatic sulfonamide 5 | hCA inhibitor, 9
TypeSmall organic molecule
Emp. Form.C7H10N2O2S
Mol. Mass.186.232
SMILESNCc1ccc(cc1)S(N)(=O)=O
Structure
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