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TargetCarbonic anhydrase 2
LigandBDBM50377332
Substrate/Competitorn/a
Meas. Tech.ChEMBL_479525
Ki 12±n/a nM
Citation Cecchi ACiani LWinum JYMontero JLScozzafava ARistori SSupuran CT Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes. Bioorg Med Chem Lett 18:3475-80 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrase 2
Synonyms:CA-II | CA2 | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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  Blast E-value cutoff:
BDBM50377332
NameBDBM50377332
Synonyms:CHEMBL436648
TypeSmall organic molecule
Emp. Form.C16H24ClN4O3S2
Mol. Mass.419.97
SMILESCC1(C)CC(CC(C)(C)N1[O])NC(=S)Nc1ccc(cc1Cl)S(N)(=O)=O |^1:10|
Structure
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