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PDB code 3MKE

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SHV-1 beta-lactamase

  (265/265 = 100%)
(Klebsiella pneumoniae (Enterobacteria))
BDBM50370963
PNG
(CEFTAZIDIME BATSI)
Show SMILES CC(C)(O\N=C(/C(=O)NCB(O)O)c1csc(N)n1)C(O)=O
Show InChI InChI=1S/C10H15BN4O6S/c1-10(2,8(17)18)21-15-6(5-3-22-9(12)14-5)7(16)13-4-11(19)20/h3,19-20H,4H2,1-2H3,(H2,12,14)(H,13,16)(H,17,18)/b15-6-
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cells


Antimicrob Agents Chemother 51: 1577-9 (2007)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
SHV-5 extended spectrum beta-lactamase

  (260/265 = 98%)
(Escherichia coli)
BDBM50370963
PNG
(CEFTAZIDIME BATSI)
Show SMILES CC(C)(O\N=C(/C(=O)NCB(O)O)c1csc(N)n1)C(O)=O
Show InChI InChI=1S/C10H15BN4O6S/c1-10(2,8(17)18)21-15-6(5-3-22-9(12)14-5)7(16)13-4-11(19)20/h3,19-20H,4H2,1-2H3,(H2,12,14)(H,13,16)(H,17,18)/b15-6-
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
4.50E+3n/an/an/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Binding affinity at Beta-lactamase SHV5 expressed in Escherichia coli DH10B cells


Antimicrob Agents Chemother 51: 1577-9 (2007)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output