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PDB code 2ZM3

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor

  (306/306 = 100%)
(Homo sapiens (Human))
BDBM28046
PNG
((4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]...)
Show SMILES Brc1ccc2C(=O)NC(=O)C(=CNc3ccc(CN4CCCC4)cc3)c2c1 |w:11.11|
Show InChI InChI=1S/C21H20BrN3O2/c22-15-5-8-17-18(11-15)19(21(27)24-20(17)26)12-23-16-6-3-14(4-7-16)13-25-9-1-2-10-25/h3-8,11-12,23H,1-2,9-10,13H2,(H,24,26,27)/b19-12-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PDB
Article
PubMed
n/an/a 2.42E+3n/an/an/an/a7.522



Wyeth Research



Assay Description
Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...


Bioorg Med Chem Lett 18: 3641-5 (2008)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Similar Ligands in BindingDB*

Found 1 hit Enzyme Inhibition Constant Data.   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor

  (306/306 = 100%)
(Homo sapiens (Human))
BDBM28076
PNG
((4Z)-6-bromo-4-[({4-[(dimethylamino)methyl]phenyl}...)
Show SMILES CN(C)Cc1ccc(NC=C2C(=O)NC(=O)c3ccc(Br)cc23)cc1 |w:9.8|
Show InChI InChI=1S/C19H18BrN3O2/c1-23(2)11-12-3-6-14(7-4-12)21-10-17-16-9-13(20)5-8-15(16)18(24)22-19(17)25/h3-10,21H,11H2,1-2H3,(H,22,24,25)/b17-10-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 7.17E+3n/an/an/an/a7.522



Wyeth Research



Assay Description
Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...


Bioorg Med Chem Lett 18: 3641-5 (2008)

More data for this
Ligand-Target Pair

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output