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PDB code 1ZNC

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 5 hits Enzyme Inhibition Constant Data   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26992
PNG
(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Show SMILES [O-]S([O-])(=O)=O
Show InChI InChI=1S//
PDB
MMDB

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PDB
Article
PubMed
9.00E+6 -11.5n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26992
PNG
(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Show SMILES [O-]S([O-])(=O)=O
Show InChI InChI=1S//
PDB
MMDB

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PDB
Article
PubMed
9.00E+6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5769-73 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26992
PNG
(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Show SMILES [O-]S([O-])(=O)=O
Show InChI InChI=1S//
PDB
MMDB

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AffyNet 
PDB
Article
PubMed
9.00E+6n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26992
PNG
(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Show SMILES [O-]S([O-])(=O)=O
Show InChI InChI=1S//
PDB
MMDB

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UniProtKB/SwissProt

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PDB
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AffyNet 
PDB
Article
PubMed
9.00E+6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against human Carbonic anhydrase IV


Bioorg Med Chem Lett 15: 567-71 (2005)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26992
PNG
(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Show SMILES [O-]S([O-])(=O)=O
Show InChI InChI=1S//
PDB
MMDB

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AffyNet 
PDB
Article
PubMed
4.40E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory constant against carbonic anhydrase IV


Bioorg Med Chem Lett 14: 4563-7 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Similar Ligands in BindingDB*

Found 2 hits Enzyme Inhibition Constant Data.   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26991
PNG
(CHEMBL1689285 | HSO3- | bisulfite | hydrogen sulfi...)
Show SMILES OS([O-])=O
Show InChI InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1
PDB
MMDB

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CHEMBL
KEGG
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PC cid
PC sid
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AffyNet 
Article
PubMed
1.32E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5769-73 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Carbonic anhydrase 4

  (266/266 = 100%)
(Homo sapiens (human))
BDBM26991
PNG
(CHEMBL1689285 | HSO3- | bisulfite | hydrogen sulfi...)
Show SMILES OS([O-])=O
Show InChI InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1
PDB
MMDB

Reactome pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
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Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.32E+7 -10.5n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (docked)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output