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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, AMPA' and Ligand = 'BDBM50107595'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, AMPA


(Mus musculus)
BDBM50107595
PNG
((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...)
Show SMILES N[C@@H](Cn1c2CCCc2c(=O)[nH]c1=O)C(O)=O |r|
Show InChI InChI=1/C10H13N3O4/c11-6(9(15)16)4-13-7-3-1-2-5(7)8(14)12-10(13)17/h6H,1-4,11H2,(H,15,16)(H,12,14,17)/t6-/s2
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CHEMBL
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PC cid
PC sid
PDB
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AffyNet 
Article
PubMed
109n/an/an/an/an/an/an/an/a



Universita' degli Studi di Siena

Curated by ChEMBL


Assay Description
Binding affinity towards GluR1 receptor from rat brain


J Med Chem 44: 4501-4 (2001)

More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, AMPA


(Mus musculus)
BDBM50107595
PNG
((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...)
Show SMILES N[C@@H](Cn1c2CCCc2c(=O)[nH]c1=O)C(O)=O |r|
Show InChI InChI=1/C10H13N3O4/c11-6(9(15)16)4-13-7-3-1-2-5(7)8(14)12-10(13)17/h6H,1-4,11H2,(H,15,16)(H,12,14,17)/t6-/s2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.49E+4n/an/an/an/a



Universita' degli Studi di Siena

Curated by ChEMBL


Assay Description
The potency at recombinant rat AMPA-R was measured on GluR1 receptor expressed in Xenopus Laevis oocytes


J Med Chem 44: 4501-4 (2001)

More data for this
Ligand-Target Pair