Compounds in cluster

7 similar compounds to monomer 16114

Wt: 443.3 BDBM15341	Wt: 403.3 BDBM16115	Wt: 415.3 BDBM16124	Wt: 403.3 BDBM16116	Wt: 425.3 BDBM16117
Wt: 415.3 BDBM16122	Wt: 415.3 BDBM16123

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 15341,16115,16116,16117,16122,16123,16124
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16115 (3-{[4-(3-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16116 (3-{[4-(2-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16117 (3-{[2,3,5,6-tetrafluoro-4-(2-methoxyphenyl)phenyl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM15341 (3-({2,6-difluoro-4-[3-(trifluoromethoxy)phenyl]phe...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars AffyNet	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	8.0	30
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 49: 1239-47 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16123 (3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16124 (4-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (human))	BDBM16122 (3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...) Show SMILES Show InChI	PDB MMDB Reactome pathway SMPDB pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	8.0	25
4SC AG					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 267-70 (2006)
4SC AG					More data for this Ligand-Target Pair				3D Structure (docked)