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BDBM84468 Mannostatin analogue, 4b::Meso-aminocyclopentitetrol, 2a

SMILES: N[C@@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H]1O

InChI Key: InChIKey=LZCRRHQKPAEPKL-CTPMEXECNA-N

Data: 2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84468   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84468
PNG
(Mannostatin analogue, 4b | Meso-aminocyclopentitet...)
Show SMILES N[C@@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2/t1-,2+,3-,4+,5-
Reactome pathway
SMPDB pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
6.60E+3 -7.35n/an/an/an/an/a5.637



University of Georgia





Citation and Details
More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Homo sapiens (Human))
BDBM84468
PNG
(Mannostatin analogue, 4b | Meso-aminocyclopentitet...)
Show SMILES N[C@@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2/t1-,2+,3-,4+,5-
Reactome pathway
SMPDB pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
5.00E+4 -6.10n/an/an/an/an/a5.637



University of Georgia





Citation and Details
More data for this
Ligand-Target Pair
Golgi alpha-mannosidase II


(Drosophila melanogaster (Fruit fly))
BDBM84468
PNG
(Mannostatin analogue, 4b | Meso-aminocyclopentitet...)
Show SMILES N[C@@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2/t1-,2+,3-,4+,5-
PDB
MMDB

Reactome pathway
SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
MMDB
PDB
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



University of Toronto



Assay Description
The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)