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BDBM50246553 CHEMBL462228::N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine::N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazine-8-amine

SMILES: Clc1ccccc1Nc1ncc(-c2ccccc2)n2cncc12

InChI Key: InChIKey=NNBICZMPIJMWGC-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246553   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (human))
BDBM50246553
PNG
(CHEMBL462228 | N-(2-chlorophenyl)-5-phenylimidazo[...)
Show SMILES Clc1ccccc1Nc1ncc(-c2ccccc2)n2cncc12
Show InChI InChI=1S/C18H13ClN4/c19-14-8-4-5-9-15(14)22-18-17-10-20-12-23(17)16(11-21-18)13-6-2-1-3-7-13/h1-12H,(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Kissei Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Inhibition of LCK (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)