BindingDB logo
myBDB logout

BDBM50175432 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID::5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid::CHEMBL199544

SMILES: OC(=O)c1ccc(o1)-c1ccc(cc1Cl)[N+]([O-])=O

InChI Key: InChIKey=HDIHNBCCQWMVBW-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175432   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175432
PNG
(5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID | 5-(2-ch...)
Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C11H6ClNO5/c12-8-5-6(13(16)17)1-2-7(8)9-3-4-10(18-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
DrugBank
MMDB
PDB
Article
PubMed
n/an/a 3.83E+4n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Co(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175432
PNG
(5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID | 5-(2-ch...)
Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C11H6ClNO5/c12-8-5-6(13(16)17)1-2-7(8)9-3-4-10(18-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
DrugBank
MMDB
PDB
Article
PubMed
n/an/a 4.29E+4n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Ni(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175432
PNG
(5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID | 5-(2-ch...)
Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C11H6ClNO5/c12-8-5-6(13(16)17)1-2-7(8)9-3-4-10(18-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
DrugBank
MMDB
PDB
Article
PubMed
n/an/a 4.86E+4n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Fe(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))
BDBM50175432
PNG
(5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID | 5-(2-ch...)
Show SMILES OC(=O)c1ccc(o1)-c1ccc(cc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C11H6ClNO5/c12-8-5-6(13(16)17)1-2-7(8)9-3-4-10(18-9)11(14)15/h1-5H,(H,14,15)
PDB
MMDB

SMPDB pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
DrugBank
MMDB
PDB
Article
PubMed
n/an/a 1.56E+3n/an/an/an/an/an/a



Graduate School of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Mn(II) form of Escherichia coli MetAP


Bioorg Med Chem Lett 15: 5386-91 (2005)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)