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BDBM50026472 (CH3)2SO::(methanesulfinyl)methanedimethyl sulfoxide::CHEMBL504::DIMETHYL SULFOXIDE::Dimethylsulfoxid::S(O)Me2::dimethyl sulfur oxide::dimethyl sulphoxide::dmso::methylsulfinylmethane::sulfinylbis(methane)

SMILES: CS(C)=O

InChI Key: InChIKey=IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Data: 1 KI  7 Kd

PDB links: 1323 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50026472   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Choline Acetyltransferase


(RAT)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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2.50E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(com)


J Med Chem 28: 1309-13 (1985)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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n/an/an/a 6.10E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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n/an/an/a 9.21E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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PubMed
n/an/an/a 6.50E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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n/an/an/a 5.41E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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PubMed
n/an/an/a 6.48E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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PubMed
n/an/an/a 7.83E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
PDB
MMDB

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PubMed
n/an/an/a 7.19E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair