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BDBM26978 BDBM50098540::CHEMBL1362::CHEMBL1528::CHEMBL1644027::F-::fluoride::fluoride ion

SMILES: [F-]

InChI Key: InChIKey=MOSFIJXAXDLOML-UHFFFAOYSA-N

Data: 55 KI

PDB links: 43 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 26978   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic Anhydrase XV


(Mus musculus (mouse))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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5.44E+4 -5.72n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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7.00E+4n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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7.00E+4 -5.57n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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7.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5769-73 (2004)

More data for this
Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI)


(Homo sapiens (Human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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6.00E+5n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Alpha carbonic anhydrase


(Stylophora pistillata)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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6.20E+5n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
β-Carbonic anhydrase (βCA)


(Helicobacter pylori)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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6.70E+5n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...


J Enzyme Inhib Med Chem 28: 388-91 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Stylophora pistillata)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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9.20E+5n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Astrosclerin-3


(Astrosclera willeyana)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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9.40E+5n/an/an/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...


Bioorg Med Chem Lett 22: 1314-6 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase 7


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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1.24E+6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA7


Bioorg Med Chem Lett 16: 3139-43 (2006)

More data for this
Ligand-Target Pair
Carbonic Anhydrase XIII


(Mus musculus (mouse))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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3.00E+6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
Alpha-carbonic anhydrase


(Helicobacter pylori (strain G27))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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4.08E+6 -3.20n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
α-Carbonic anhydrase (αCA)


(Helicobacter pylori)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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4.08E+6n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...


J Enzyme Inhib Med Chem 28: 388-91 (2013)

More data for this
Ligand-Target Pair
Alpha-carbonic anhydrase


(Vibrio cholerae)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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8.00E+6 -2.81n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
Beta-carbonic anhydrase


(Vibrio cholerae)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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8.70E+6 -2.76n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Vibrio cholerae)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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2.13E+7 -2.24n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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4.80E+7n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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4.80E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX


Bioorg Med Chem Lett 14: 5769-73 (2004)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>1.00E+8n/an/an/an/an/an/an/an/a



Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for...


Bioorg Med Chem 23: 4831-8 (2015)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>2.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory constant against Zn-Cam (Methanosarcina thermophila)


Bioorg Med Chem Lett 14: 4563-7 (2004)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>2.00E+8n/an/an/an/an/an/an/an/a



Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow method


Bioorg Med Chem 23: 4831-8 (2015)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>2.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4402-6 (2014)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26978
PNG
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>2.00E+8n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse, CNR, Via Pietro Castellino 81, Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay


Bioorg Med Chem 23: 4405-9 (2015)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>2.00E+8n/an/an/an/an/an/an/an/a



Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL


Assay Description
Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay


Bioorg Med Chem Lett 23: 4067-71 (2013)

More data for this
Ligand-Target Pair
Carbonic Anhydrase VA


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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2.41E+8n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 5 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>3.00E+8n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
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>3.00E+8>-0.701n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3


Bioorg Med Chem Lett 21: 3591-5 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 22: 7142-5 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 22: 7142-5 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Kochi Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method


Bioorg Med Chem Lett 23: 256-60 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Kochi Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method


Bioorg Med Chem Lett 23: 256-60 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1626-30 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1636-8 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1636-8 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
PDB
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>3.00E+8n/an/an/an/an/an/an/an/a



Istituto di Biochimica delle Proteine (IBP)

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay


Bioorg Med Chem 21: 1465-9 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8>-0.701n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5


Bioorg Med Chem 19: 1847-51 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Ondokuz Mayis University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 by Lineweaver-Burk curves


Bioorg Med Chem 19: 744-8 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse, CNR, Via Pietro Castellino 81, Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assay


Bioorg Med Chem 23: 4405-9 (2015)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse (IBBR)-CNR, via P. Castellino 111, 80131 Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4389-96 (2014)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3


Bioorg Med Chem Lett 21: 3591-5 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8>-0.701n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
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>3.00E+8n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse (IBBR)-CNR, via P. Castellino 111, 80131 Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4389-96 (2014)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
PDB
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>3.00E+8n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5


Bioorg Med Chem 19: 1847-51 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
PDB
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>3.00E+8n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26978
PNG
(BDBM50098540 | CHEMBL1362 | CHEMBL1528 | CHEMBL164...)
Show InChI InChI=1S//
PDB
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>3.00E+8>-0.701n/an/an/an/an/a7.520



TBA



Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 3413-7 (2016)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 55 total )  |  Next  |  Last  >>