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BDBM24256 (2S)-2-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}butanoic acid::Amino acid analog, 4f

SMILES: N[C@@H](CCC(=O)Nc1ccc(OCc2ccccc2)cc1)C(O)=O

InChI Key: InChIKey=BYSBXIPCDJNEBG-XISACWJONA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24256   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM24256
PNG
((2S)-2-amino-4-{[4-(benzyloxy)phenyl]carbamoyl}but...)
Show SMILES N[C@@H](CCC(=O)Nc1ccc(OCc2ccccc2)cc1)C(O)=O |r|
Show InChI InChI=1/C18H20N2O4/c19-16(18(22)23)10-11-17(21)20-14-6-8-15(9-7-14)24-12-13-4-2-1-3-5-13/h1-9,16H,10-12,19H2,(H,20,21)(H,22,23)/t16-/s2
PDB
MMDB

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PC cid
PC sid
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Similars

AffyNet 
PDB
Article
PubMed
n/an/a 20n/an/an/an/a7.522



Berlex Biosciences



Assay Description
Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)