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BDBM13529 N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid::SULFAMIC ACID Analog 13

SMILES: Cn1nc(cc1NS(O)(=O)=O)-c1ccccc1

InChI Key: InChIKey=OTZLVSGSRPNRFT-UHFFFAOYSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13529   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-Tyrosine Phosphatase 1B (PTP1B)


(Homo sapiens (human))
BDBM13529
PNG
(N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid...)
Show SMILES Cn1nc(cc1NS(O)(=O)=O)-c1ccccc1
Show InChI InChI=1S/C10H11N3O3S/c1-13-10(12-17(14,15)16)7-9(11-13)8-5-3-2-4-6-8/h2-7,12H,1H3,(H,14,15,16)
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
DrugBank
PDB
Article
PubMed
>5.00E+5>-4.45n/an/an/an/an/a7.022



Procter & Gamble Pharmaceuticals



Assay Description
The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)