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BDBM13113 CGS 27023A Analog 41::N-hydroxy-2-[(4-methoxybenzene)(pyridin-4-ylmethyl)sulfonamido]acetamide

SMILES: COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccncc1

InChI Key: InChIKey=BWTYNJYIHZVAOW-UHFFFAOYSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13113   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Stromelysin-1


(Homo sapiens (human))
BDBM13113
PNG
(CGS 27023A Analog 41 | N-hydroxy-2-[(4-methoxybenz...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccncc1
Show InChI InChI=1S/C15H17N3O5S/c1-23-13-2-4-14(5-3-13)24(21,22)18(11-15(19)17-20)10-12-6-8-16-9-7-12/h2-9,20H,10-11H2,1H3,(H,17,19)
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MMDB

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PC sid
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Similars

AffyNet 
PDB
Article
PubMed
192 -9.53n/an/an/an/an/a7.537



Novartis Pharmaceuticals



Assay Description
Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)