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Affinity Unit: nM uM
 1-deoxy-D-xylulose 5-phosphate reductoisomerase [ 9 ] HIV-1 Protease Mutant (V82A) [ 5 ]
 11-beta-hydroxysteroid dehydrogenase 1 [ 403 ] HIV-1 Protease Mutant (V82I) [ 1 ]
 11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) [ 78 ] HIV-1 Protease Mutant K-60C [ 15 ]
 11-beta-hydroxysteroid dehydrogenase 2 [ 34 ] HIV-1 Protease Mutant M1 (L10I, G48V, I54V, L63P, V82A) [ 19 ]
 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) [ 19 ] HIV-1 Protease Mutant M2 (D30N, L63P, N88D) [ 19 ]
 12-Lipoxygenase (12-LOX) [ 17 ] HIV-1 Protease Mutant M3 (L10I, L63P, A71V, G73S, I84V, L90M) [ 19 ]
 15-Lipoxygenase-2 (15-LOX-2) [ 5 ] HIV-1 Protease Mutant Q-60C [ 11 ]
 17-beta-Hydroxysteroid Dehydrogenase 1 (17-beta-HSD1) [ 45 ] HIV-1 Protease Mutant V-18C [ 27 ]
 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) [ 9 ] HIV-1 Protease Mutant V6 [ 4 ]
 17-beta-hydroxysteroid dehydrogenase type 3 [ 15 ] HIV-1 Protease Mutant V6(46) [ 4 ]
 20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (H222S) [ 1 ] HIV-1 Protease Mutant V6(46/54/84) [ 4 ]
 20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L306A) [ 1 ] HIV-1 Protease Mutant V6(46/84) [ 4 ]
 20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L308A) [ 1 ] HIV-1 Protease Mutant V6(54) [ 4 ]
 20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L54V) [ 1 ] HIV-1 Protease Mutant V6(54/84) [ 4 ]
 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) [ 9 ] HIV-1 Protease Mutant V6(84) [ 4 ]
 3-alpha-Hydroxysteroid Dehydrogenase Type 1 (AKR1C4) [ 1 ] HIV-1 Protease Mutant, A-1 [ 4 ]
 3-phosphoinositide dependent protein kinase-1 [ 106 ] HIV-1 Protease Mutant, ANAM-11 [ 4 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) [ 43 ] HIV-1 Protease Mutant, NAM-10 [ 4 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (A162V) [ 2 ] HIV-1 Reverse Transcriptase [ 1554 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (E166D) [ 2 ] HIV-1 Reverse Transcriptase Mutant (103N/181C) [ 36 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (L159M) [ 2 ] HIV-1 Reverse Transcriptase Mutant (G190A) [ 9 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (T222A) [ 2 ] HIV-1 Reverse Transcriptase Mutant (K103N) [ 104 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (V143T) [ 2 ] HIV-1 Reverse Transcriptase Mutant (K103N/Y181C) [ 11 ]
 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (V143T/T222A) [ 2 ] HIV-1 Reverse Transcriptase Mutant (L100I) [ 61 ]
 3C-like proteinase (3CL-PRO) [ 20 ] HIV-1 Reverse Transcriptase Mutant (L100I/K103N) [ 3 ]
 3C-like proteinase (CVB3 3Cpro) [ 4 ] HIV-1 Reverse Transcriptase Mutant (P236L) [ 53 ]
 5-enolpyruvylshikimate-3-phosphate synthase [ 2 ] HIV-1 Reverse Transcriptase Mutant (V106A) [ 12 ]
 5-HT3A Serotonin Receptor [ 43 ] HIV-1 Reverse Transcriptase Mutant (V179D) [ 5 ]
 5-Lipoxygenase [ 28 ] HIV-1 Reverse Transcriptase Mutant (Y181C) [ 340 ]
 5-lipoxygenase/FLAP [ 98 ] HIV-1 Reverse Transcriptase Mutant (Y181I) [ 5 ]
 72 kDa type IV collagenase [ 237 ] HIV-1 Reverse Transcriptase Mutant (Y188L) [ 62 ]
 A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) [ 5 ] HIV-1 Reverse Transcriptase RNase H [ 30 ]
 A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) [ 5 ] HIV-1 Reverse Transcriptase RNase H Mutant (D67N/K70R/T215F/K219Q) [ 2 ]
 a4B2 nicotinic acetylcholine receptor [ 43 ] HIV-1 Reverse Transcriptase RNase H Mutant (L100I/K103N) [ 2 ]
 a7 nicotinic acetylcholine receptor [ 50 ] HIV-1 Reverse Transcriptase RNase H Mutant (V106A/Y181C) [ 2 ]
 Abhydrolase Domain-Containing Protein 6 [ 1 ] HIV-1 Reverse Transcriptase RNase H Mutant (Y181C) [ 2 ]
 ABL [ 21 ] HIV-1 Reverse Transcriptase RNase H Mutant (Y188L) [ 2 ]
 ABL Mutant (E255K) [ 7 ] HIV-2 Protease [ 22 ]
 ABL Mutant (F359V) [ 7 ] HIV-2 Reverse Transcriptase [ 5 ]
 ABL Mutant (H396P) [ 7 ] HMG-CoA reductase [ 107 ]
 ABL Mutant (M351T) [ 7 ] Homoisocitrate Dehydrogenase (HICDH) [ 12 ]
 ABL Mutant (Q252H) [ 7 ] Homoserine kinase [ 6 ]
 ABL Mutant (T315I) [ 32 ] Hormone-sensitive lipase (HSL) [ 14 ]
 ABL Mutant (T315N) [ 7 ] HSP90 and hnRNPA2/B1 [ 212 ]
 ABL Mutant (Y253F) [ 7 ] HTH-type transcriptional regulator mgrA (MgrA) [ 4 ]
 ABL1(Q252H) [ 32 ] Human herpesvirus 1 protease [ 12 ]
 Acetyl-CoA carboxylase 1 (ACC1) [ 4 ] Hyaluronidase [ 14 ]
 Acetyl-CoA carboxylase 2 (ACC2) [ 33 ] Hydroxycarboxylic acid receptor 2 [ 18 ]
 Acetyl-coenzyme A transporter 1 (AT1) [ 148 ] Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) [ 2 ]
 Acetylcholine Binding protein [ 149 ] Hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT) [ 2 ]
 Acetylcholinesterase [ 894 ] Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) [ 11 ]
 Acetylcholinesterase (AChE) [ 5 ] I-kappa-B Kinase 1 (IKK-alpha) [ 142 ]
 Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) [ 224 ] I-kappa-B Kinase 2 (IKK-beta) [ 64 ]
 Acidic fibroblast growth factor [ 11 ] IKK epsilon/TBK1 [ 40 ]
 Acidic mammalian chitinase (AMCase) [ 2 ] Immunophilin FKBP12 [ 50 ]
 AcrAB-TolC [ 3 ] IMP Cyclohydrolase (IMPCH) [ 3 ]
 Acyl Cholesterol Acyltransferase 1 (ACAT-1) [ 7 ] Indoleamine 2,3-Dioxygenase [ 108 ]
 ADAM17 [ 81 ] Induced myeloid leukemia cell differentiation protein Mcl-1 [ 10 ]
 ADAMTS-4 (Aggrecanase-1) [ 30 ] Inhibitor of NF-kappa-B kinase (IKK) [ 109 ]
 ADAMTS-5 (Aggrecanase-2) [ 65 ] Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1) [ 18 ]
 ADC-7 beta-lactamase (ADC-7) [ 2 ] Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) [ 44 ]
 Adenosine deaminase [ 59 ] Inosine-5-monophosphate dehydrogenase (IMPDH) [ 39 ]
 Adenosine Kinase (AK) [ 8 ] Inositol 1,4,5-trisphosphate 3-kinase (IP3K ) [ 24 ]
 Adenosine Phosphosulfate Reductase (APSR) [ 10 ] Insulin receptor [ 1 ]
 Adenosine receptor [ 43 ] Insulin Receptor Tyrosine Kinase (IRK) [ 100 ]
 Adenosine Receptor A1 [ 174 ] Insulin Receptor-Related Protein (INSRR) [ 6 ]
 Adenosine receptor A2A [ 248 ] Insulin-like growth factor 1 receptor (IGF1R) [ 228 ]
 Adenosine receptor A2a and A3 [ 19 ] Integrase [ 495 ]
 Adenosine Receptor A2B [ 7 ] Integrin alpha1beta1 [ 5 ]
 Adrenergic receptor [ 25 ] Integrin alpha2beta1 [ 33 ]
 Adrenergic receptor alpha [ 4 ] Integrin alpha4beta1 (VLA-4) [ 248 ]
 Adrenergic receptor beta [ 46 ] Integrin alpha4beta7 [ 71 ]
 Ah Receptor [ 8 ] Integrin alpha5beta1 [ 5 ]
 AICAR Tfase [ 19 ] Interleukin-1 receptor-associated kinase 4 [ 3 ]
 AKT/p21CIP1 [ 274 ] Interleukin-1 receptor-associated kinase 4 (IRAK4) [ 643 ]
 Aldehyde reductase [ 40 ] Interstitial collagenase [ 196 ]
 Aldo-keto reductase family 1 member C1 [ 1 ] Intestinal fatty acid-binding protein (hIFABP) [ 6 ]
 Aldo-keto reductase family 1 member C2 [ 1 ] Jumonji domain-containing protein 1A (JMJD1A) [ 6 ]
 Aldose reductase [ 7 ] Jumonji domain-containing protein 2A (JMJD2A) [ 5 ]
 Aldose Reductase (ALR2) [ 156 ] Jumonji domain-containing protein 2C (JMJD2C) [ 6 ]
 Aldose Reductase (ALR2) Mutant (C298A) [ 2 ] Jumonji/ARID domain-containing protein 1C (JARID1C) [ 6 ]
 Aldose Reductase (ALR2) Mutant (C298A/W219Y) [ 12 ] Kaposi's sarcoma-associated herpesvirus (KSHV) [ 3 ]
 ALK tyrosine kinase receptor [ 15 ] Kappa Opioid Receptor [ 94 ]
 Alpha adrenergic receptor 1A and 1B [ 12 ] Ketol-acid reductoisomerase [ 4 ]
 Alpha-(1,3)-fucosyltransferase IV [ 3 ] KIAA1363 [ 1 ]
 Alpha-(1,3)-fucosyltransferase VII [ 14 ] kinesin spindle protein [ 37 ]
 Alpha-(2,3)-(N)-sialyltransferase [ 3 ] Kinesin Spindle Protein Eg5 [ 198 ]
 alpha-Amylase [ 20 ] kinesin spindle protein Mutant (A356T) [ 2 ]
 alpha-Carbonic Anhydrase [ 17 ] kinesin spindle protein Mutant (D130V) [ 12 ]
 alpha-Chymotrypsin [ 1 ] Kynurenine Aminotransferase 1/Glutamine Transaminase K [ 2 ]
 Alpha-fucosidase [ 8 ] L-lactate dehydrogenase A [ 71 ]
 alpha-Glucosidase (alpha-Glu) [ 35 ] Lactate Dehydrogenase [ 70 ]
 Alpha-glucosidase A (α-Gal A) [ 14 ] Lck [ 250 ]
 alpha-Methylacyl-CoA Racemase [ 10 ] Lecithin-cholesterol acyltransferase (LCAT) [ 4 ]
 Aminoacyl-tRNA synthetase [ 6 ] Legumain [ 2 ]
 Aminopeptidase M [ 46 ] Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) [ 25 ]
 Anandamide amidohydrolase [ 96 ] Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) [ 19 ]
 Androgen Receptor [ 263 ] Leucyl-tRNA synthetase (LeuRS) [ 1 ]
 Angiotensin-Converting Enzyme [ 39 ] Leucyl-tRNA synthetase K510A mutant (K510A) [ 1 ]
 Angiotensin-converting enzyme, ACE [ 2 ] Leucyl-tRNA synthetase K510E mutant (K510E) [ 1 ]
 Anthrax Lethal Factor (LF) [ 246 ] Leukocyte elastase [ 65 ]
 Apoptosis regulator Bcl-2 [ 62 ] Leukotriene A4 hydrolase [ 117 ]
 Apoptosis Regulator Bcl-xL [ 78 ] Lipoxygenase [ 33 ]
 Apurinic-Apyrimidinic Endonuclease 1 (APE1) [ 47 ] Lipoxygenase-1 [ 36 ]
 Arachidonate 15-lipoxygenase [ 17 ] Liver Receptor Homolog 1 [ 23 ]
 Arginase (SmARG) [ 8 ] Liver X Receptor alpha (LXR-alpha) [ 90 ]
 Aromatase (CYP19) [ 461 ] Liver X Receptor beta (LXR-beta) [ 90 ]
 Aryl Hydrocarbon Receptor (AhR) [ 25 ] Liver X receptor beta (LXRB) [ 164 ]
 Asparaginyl Endopeptidase (AE) [ 89 ] LXR-alpha [ 114 ]
 ATP Phosphoribosyltransferase [ 11 ] Lysine-specific demthylase 5A (JARID1A) [ 25 ]
 ATP-binding cassette sub-family G member 2 [ 21 ] Macrophage colony stimulating factor receptor  [ 262 ]
 ATP-dependent clamp loaders gp44/62 [ 13 ] Macrophage colony-stimulating factor 1 (CSF-1) [ 14 ]
 ATP-dependent clamp loaders gp44/62 (R175K) [ 7 ] Macrophage colony-stimulating factor 1 receptor (c-Fms) [ 27 ]
 ATP-dependent clamp loaders gp44/62 (R175L) [ 7 ] Macrophage migration inhibitory factor (MIF) [ 18 ]
 Aurora Kinase A (Aurora-A) [ 26 ] Malate Dehydrogenase (pfMDH) [ 8 ]
 Aurora Kinase C (Aurora-C) [ 18 ] Malate dehydrogenase cytoplasmic [ 7 ]
 AXL receptor tyrosine kinase [ 4 ] Malate Dehydrogenase, mitochondrial [ 9 ]
 B-Raf Protein Kinase [ 1 ] Mammalian target of Rapamycin (mTORC1) [ 263 ]
 B-Raf Protein Kinase Mutant (V599E) [ 1 ] MAP kinase ERK1 [ 1 ]
 B-Raf Protein Kinase Mutant (V600E) [ 249 ] MAP kinase ERK2 [ 71 ]
 Bacterial Leucyl Aminopeptidase [ 19 ] MAP Kinase Kinase 1 (MEK1) [ 1 ]
 Bacteriophage T4 DNA Ligase [ 7 ] MAP kinase p38 [ 80 ]
 Basic fibroblast growth factor [ 11 ] MAP Kinase p38 alpha Mutant (G110A) [ 6 ]
 Bcl-2-related protein A1 [ 206 ] MAP Kinase p38 alpha Mutant (G110D) [ 6 ]
 Bcl-xL/BAK [ 131 ] MAP Kinase p38 beta [ 15 ]
 Beta amyloid A4 protein [ 7 ] MAP kinase signal-integrating kinase 2 [ 10 ]
 Beta-2 adrenergic receptor and beta-3 adrenergic receptor [ 25 ] MAP kinase-activated protein kinase 2 [ 48 ]
 Beta-2-microglobulin [ 7 ] MAP kinase-activated protein kinase 3 [ 4 ]
 beta-Carbonic Anhydrase [ 37 ] MAP kinase-activated protein kinase 5 [ 4 ]
 beta-glucosidase [ 7 ] MAP kinase-interacting serine/threonine-protein kinase MNK1 [ 14 ]
 Beta-hexosaminidase subunit beta (Hex B) [ 6 ] MAP-Microtubule Affinity-Regulating Kinase 3 (MARK3) [ 1 ]
 beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) [ 53 ] MAPK-Activated Protein Kinase 2 (MK2) [ 102 ]
 Beta-ketoacyl-ACP synthase (KasA) [ 17 ] Mast/stem cell growth factor receptor [ 181 ]
 Beta-ketoacyl-ACP synthase (KasA) C171Q [ 22 ] Matriptase [ 68 ]
 Beta-ketoacyl-ACP synthase III (FabH) [ 10 ] Matrix metalloproteinase (1 and 13) [ 124 ]
 Beta-lactamase [ 14 ] Matrix metalloproteinase 10 [ 7 ]
 Beta-lactamase (CTX-M) [ 14 ] Matrix metalloproteinase 12 [ 9 ]
 Beta-lactamase (TEM-1) [ 3 ] Matrix metalloproteinase 14 [ 9 ]
 Beta-lactamase AmpC [ 63 ] Matrix metalloproteinase 7 [ 3 ]
 Beta-mannosidase [ 25 ] Matrix Metalloproteinase-10 (MMP-10) [ 6 ]
 beta-Secretase (BACE-1) [ 75 ] Matrix Metalloproteinase-12 (MMP-12) [ 71 ]
 Beta-secretase 1 [ 428 ] Matrix Metalloproteinase-13 (MMP-13) [ 116 ]
 Beta-secretase 2 (BACE2) [ 124 ] Matrix Metalloproteinase-14 (MMP-14) [ 13 ]
 Bfl-1 [ 44 ] Matrix Metalloproteinase-7 (MMP-7) [ 34 ]
 Bifunctional protein (GlmU) [ 20 ] Matrix Metalloproteinase-8 (MMP-8) [ 13 ]
 Bile acid receptor FXR [ 37 ] MBT domain-containing protein 1 (MBTD1) [ 25 ]
 Biotin Carboxylase [ 14 ] Mcl-1 (residues 172-327) [ 6 ]
 Bone Morphogenetic Protein Receptor type II (BMPR2) [ 6 ] Melanin-concentrating hormone receptor [ 27 ]
 Botulinum Neurotoxin Type A [ 133 ] Metallo-beta-lactamase [ 13 ]
 Butyrylcholine esterase [ 472 ] Methionine Aminopeptidase (MAP) [ 20 ]
 Butyrylcholinesterase [ 102 ] Methionine aminopeptidase 2 [ 299 ]
 c-Jun N-terminal kinase, JNK [ 442 ] Methionine Aminopeptidase Type 1 (MetAP1) [ 14 ]
 c-Kit [ 6 ] Methionine aminopeptidase Type 2 (MetAP2) [ 12 ]
 C-terminal-binding protein 1 (CtBP1) [ 3 ] Methyl-lysine binding protein (53BP1) [ 26 ]
 C-terminal-binding protein 2 (CtBP2) [ 2 ] Methylthioadenosine Nucleosidase (MTAN) [ 40 ]
 Calcitonin gene-related peptide (CGRP)Calcitonin gene-related peptide (CGRP) [ 5 ] Methylthioadenosine Nucleosidase(MTAN) [ 17 ]
 Calcium-dependent protein kinase 1 [ 30 ] Methylthioadenosine Phosphorylase (MTAP) [ 11 ]
 Calcium-Sensing Receptor (CaSR) [ 44 ] Mineralocorticoid Receptor (MR) [ 22 ]
 Calcium/calmodulin-dependent protein kinase II [ 3 ] Mitogen-activated protein kinase 10 [ 49 ]
 Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKKB) P274E [ 1 ] Mitogen-Activated Protein Kinase 10 (JNK3) [ 54 ]
 Calpain-1 [ 21 ] Mitogen-activated protein kinase 14 [ 523 ]
 Calpain-2 [ 10 ] Mitogen-activated protein kinase 15 [ 9 ]
 CaM Kinase II [ 42 ] Mitogen-activated protein kinase 9 [ 91 ]
 CaM-kinase kinase beta [ 1 ] Mitogen-activated protein kinase kinase kinase 1 [ 1 ]
 cAMP-Dependent Protein Kinase (PKA) [ 457 ] Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) [ 4 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (1) [ 5 ] Mitogen-activated protein kinase kinase kinase 8 [ 90 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (2) [ 5 ] Mitogen-activated protein kinase kinase kinase kinase 4 [ 1 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (3) [ 5 ] Mixed Lineage Kinase 1 (MLK1) [ 37 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (4) [ 5 ] Mixed Lineage Kinase 2 (MLK2) [ 8 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (1) [ 5 ] Mixed Lineage Kinase 3 (MLK3) [ 37 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (2) [ 1 ] MKP-3 [ 45 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (3) [ 3 ] ML-IAP-BIR [ 32 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR3 [ 5 ] Monoamine oxidase [ 419 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR3 (1) [ 5 ] Monoamine Oxidase Type A (MAO-A) [ 48 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR4 [ 5 ] Monoamine Oxidase Type B (MAO-B) [ 165 ]
 cAMP-Dependent Protein Kinase (PKA) Mutant PKAR5 [ 5 ] Monoamine oxidase type B (MAO-B) Mutant (I199F) [ 5 ]
 cAMP-dependent protein kinase type I-alpha regulatory subunit [ 3 ] Monocarboxylate Transporter 1 [ 43 ]
 cAMP-specific 3',5'-cyclic phosphodiesterase 4A [ 156 ] Monoglyceride Lipase (MGL) [ 22 ]
 Cannabinoid CB1 receptor/orexin receptor 1 complex [ 164 ] MPI protein [ 462 ]
 Cannabinoid receptor [ 151 ] MRCK alpha [ 5 ]
 Carbamoyl-phosphate synthase (H353N) [ 6 ] Mu-type opioid receptor (Mu) [ 98 ]
 Carbonic anhydrase [ 12 ] mu/kappa opioid receptor [ 5 ]
 Carbonic Anhydrase (hpCA) [ 47 ] MurC [ 6 ]
 Carbonic Anhydrase (mtCA 1) [ 37 ] MurD [ 37 ]
 Carbonic Anhydrase (mtCA 3) [ 37 ] MurE [ 6 ]
 Carbonic anhydrase 13 (CA XIII) [ 6 ] MurF [ 6 ]
 Carbonic Anhydrase 2 (Can2) [ 37 ] Myeloperoxidase (MPO) [ 5 ]
 Carbonic anhydrase 6 (CA VI) [ 17 ] Myosin light chain kinase, smooth muscle [ 18 ]
 Carbonic Anhydrase I [ 507 ] N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) [ 6 ]
 Carbonic Anhydrase II [ 700 ] NAD synthetase [ 4 ]
 Carbonic Anhydrase II Mutant (F131V) [ 11 ] NAD-dependent deacetylase sirtuin 2 [ 20 ]
 Carbonic Anhydrase III [ 54 ] NAD-Dependent Deacetylase Sirtuin-1 [ 28 ]
 Carbonic Anhydrase IV [ 287 ] NADPH-dependent enoyl-ACP reductase (FabI) [ 3 ]
 Carbonic Anhydrase IX [ 283 ] Neprilysin [ 29 ]
 Carbonic Anhydrase V [ 5 ] Neuraminidase A [ 268 ]
 Carbonic Anhydrase VA [ 154 ] Neuraminidase B [ 181 ]
 Carbonic Anhydrase VB [ 108 ] Neurokinin 1 receptor [ 23 ]
 Carbonic Anhydrase VI [ 85 ] Neuronal acetylcholine receptor [ 12 ]
 Carbonic Anhydrase VII [ 70 ] Neuropeptide Y receptor type 5 ( NPY Y5) [ 2 ]
 Carbonic Anhydrase XII [ 74 ] Neuropeptide Y receptor type 5 (NPY Y5) [ 25 ]
 Carbonic Anhydrase XIII [ 51 ] Neurotrophic tyrosine kinase receptor type 2 [ 2 ]
 Carbonic Anhydrase XIV [ 58 ] Nicotinamide adenine dinucleotide synthetase (NADs) [ 81 ]
 Carbonic Anhydrase XV [ 73 ] Nicotinate-nucleotide adenylyltransferase (NadD) [ 77 ]
 Carboxylesterase 1 [ 271 ] Nitric oxide synthase (inducible and endothelial) [ 14 ]
 Carboxylesterase 2 (intestine, liver) [ 146 ] Nitric Oxide Synthase, brain Mutant (D597N) [ 3 ]
 Carboxypeptidase A1 [ 15 ] Nitric Oxide Synthase, brain Mutant (D597N/M336V) [ 4 ]
 Casein Kinase I [ 12 ] Nitric Oxide Synthase, endothelial [ 24 ]
 Casein kinase I isoform alpha (CK1 Alpha) [ 4 ] Nitric Oxide Synthase, endothelial Mutant (N368D) [ 3 ]
 Casein kinase I/MDM2 [ 180 ] Nitric Oxide Synthase, inducible [ 14 ]
 Casein Kinase II [ 33 ] Nitric-oxide synthase (endothelial and brain) [ 31 ]
 Casein kinase II alpha/beta [ 12 ] Nitric-oxide synthase, brain [ 24 ]
 Caspase-1 [ 145 ] Nociceptin receptor [ 172 ]
 Caspase-2 [ 24 ] Nociceptin/mu opioid receptor [ 74 ]
 Caspase-3 [ 412 ] Non-receptor tyrosine-protein kinase TYK2 [ 3 ]
 Caspase-4 [ 17 ] Non-structural protein 5B (NS5B) [ 16 ]
 Caspase-5 [ 9 ] Norepinephrine transporters (NET) [ 56 ]
 Caspase-6 [ 75 ] NS3 Protease [ 1 ]
 Caspase-7 [ 133 ] Oligosaccharyl transferase (OT) [ 9 ]
 Caspase-8 [ 132 ] Opioid receptor [ 3 ]
 Caspase-9 [ 8 ] Orexin receptor 1 [ 190 ]
 Cathepsin (B and K) [ 161 ] Orexin receptor 2 [ 218 ]
 Cathepsin (H and K) [ 468 ] Orotidine Monophosphate Decarboxylase (ODCase) [ 23 ]
 Cathepsin B [ 185 ] p38 delta/gamma [ 8 ]
 Cathepsin B-Like Cysteine Protease (TbcatB) [ 56 ] p53-Binding Protein HDMX [ 25 ]
 Cathepsin D [ 314 ] Pancreatic alpha-amylase [ 6 ]
 Cathepsin H [ 4 ] Pantothenate synthetase [ 5 ]
 Cathepsin K [ 144 ] Papain [ 50 ]
 Cathepsin L [ 114 ] Pepsin [ 5 ]
 Cathepsin L1 [ 471 ] Pepsin A [ 21 ]
 Cathepsin S [ 633 ] Peptide Deformylase [ 12 ]
 Cathepsin V [ 45 ] Peptidyl-prolyl cis-trans isomerase [ 13 ]
 Cathepsin Z [ 3 ] Peripheral-Type Benzodiazepine Receptor [ 10 ]
 Cdc7 Kinase [ 101 ] Peroxisome Proliferator-Activated Receptor alpha [ 193 ]
 CDK1/Cyclin E [ 32 ] Peroxisome Proliferator-Activated Receptor delta [ 153 ]
 CDK2/CDK4 [ 215 ] Peroxisome Proliferator-Activated Receptor gamma [ 110 ]
 CDK6/cyclin D2 [ 267 ] PHD finger protein 1 (PHF1) [ 25 ]
 CDK7/Cyclin H/MNAT1 [ 12 ] PHD finger protein 19 (PHF19) [ 25 ]
 CDK8/Cyclin C [ 8 ] PHD finger protein 23 (PHF23) [ 25 ]
 CDK9/Cyclin K [ 22 ] Phenylethanolamine N-methyltransferase [ 31 ]
 Cell Division Cycle 2-Like 1(CDC2L1) [ 7 ] phosphatase Cdc25 [ 18 ]
 Cell Division Cycle 2-Like 2 (CDC2L2) [ 7 ] Phosphatidylinositol 3-kinase catalytic subunit type 3 [ 1 ]
 Cell division cycle 2-like protein kinase 6 [ 11 ] Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide [ 7 ]
 cFMS -Tie-2 Chimera [ 7 ] Phosphodiesterase (TcrPDEC) [ 14 ]
 cGMP-dependent 3',5'-cyclic phosphodiesterase [ 18 ] Phosphodiesterase 1 [ 10 ]
 cGMP-Dependent Protein Kinase [ 23 ] Phosphodiesterase 10A [ 97 ]
 cGMP-inhibited 3',5'-cyclic phosphodiesterase A [ 33 ] Phosphodiesterase 4 and 5 (PDE4 and PDE5) [ 50 ]
 cGMP-inhibited 3',5'-cyclic phosphodiesterase B [ 29 ] Phosphodiesterase 4D (PDE4D) [ 4 ]
 Checkpoint Kinase (Chk1) [ 206 ] Phosphodiesterase 8 [ 11 ]
 Checkpoint Kinase (Chk2) [ 15 ] Phosphodiesterase 9A2 [ 43 ]
 Checkpoint kinase Chk1 (CHK1) [ 65 ] Phosphodiesterase Type 10 (PDE10A) [ 59 ]
 Chitinase [ 29 ] Phosphodiesterase Type 11 (PDE11A) [ 10 ]
 Chitinase (chiA1) [ 9 ] Phosphodiesterase Type 2 (PDE2A) [ 10 ]
 Chitinase Mutant (A217G) [ 3 ] Phosphodiesterase Type 3 (PDE3A) [ 40 ]
 Chitinase Mutant (D175A) [ 3 ] Phosphodiesterase Type 3 (PDE3B) [ 52 ]
 Chitinase Mutant (D246A) [ 1 ] Phosphodiesterase Type 4 (PDE4B) [ 31 ]
 Chitinase Mutant (E177A) [ 1 ] Phosphodiesterase Type 4 (PDE4C) [ 2 ]
 Chitinase Mutant (E322A) [ 3 ] Phosphodiesterase Type 4 (PDE4D) [ 139 ]
 Chitinase Mutant (M243A) [ 3 ] Phosphodiesterase Type 5 (PDE5A) [ 13 ]
 Chitinase Mutant (R301K) [ 3 ] Phosphodiesterase Type 5 (PDE5A) Mutant (661-681 deletion) [ 3 ]
 Chitinase Mutant (T138A) [ 3 ] Phosphodiesterase Type 5 (PDE5A) Mutant (663-678 deletion) [ 3 ]
 Chitinase Mutant (Y245F) [ 2 ] Phosphodiesterase Type 6 (PDE6) [ 7 ]
 Cholecystokinin receptor [ 34 ] Phosphodiesterase Type 7 (PDE7B) [ 10 ]
 Cholesteryl ester transfer protein (CETP) [ 23 ] Phosphodiesterase Type 9 (PDE9A) [ 10 ]
 Chromobox protein homolog 7 (CBX7) [ 25 ] Phosphodiesterase, PDE1/PDE5 [ 29 ]
 Chymase [ 33 ] Phosphoehtnaolamine Methyltransferases 1 (PMT1) [ 22 ]
 Chymotrypsin [ 39 ] Phosphoehtnaolamine Methyltransferases 2 (PMT2) [ 14 ]
 cIAP-1 BIR3 [ 10 ] Phosphoinositide 3-Kinase (PI3K), alpha [ 109 ]
 cIAP-2 BIR3 [ 10 ] Phosphoinositide 3-Kinase (PI3K), alpha Mutant (E545K) [ 1 ]
 cIAP1-BIR3 [ 5 ] Phosphoinositide 3-Kinase (PI3K), alpha Mutant (H1047R) [ 1 ]
 cIAP2-BIR3 [ 3 ] Phosphoinositide 3-Kinase (PI3K), beta [ 8 ]
 CLK1 [ 16 ] Phosphoinositide 3-Kinase (PI3K), delta [ 8 ]
 Coagulation factor IX and X [ 92 ] Phosphoinositide 3-Kinase (PI3K), gamma [ 27 ]
 Coagulation Factor VIII [ 16 ] Phospholipase A2 [ 4 ]
 Coagulation factor X [ 3 ] Phospholipase A2, major isoenzyme [ 21 ]
 Coagulation factor X and plasma kallikrein [ 58 ] Phospholipase A2, membrane associated [ 32 ]
 Coagulation factor X/antithrombin III [ 1182 ] Phosphorylase Kinase [ 13 ]
 Coagulation factor XI [ 430 ] PI3-kinase p110-alpha/p85-alpha [ 361 ]
 Collagenase [ 296 ] PI3-kinase p110-gamma subunit [ 51 ]
 Collagenase (ChC) [ 187 ] PI3K p110 beta/p85 alpha [ 6 ]
 Complement C1 [ 10 ] PIM-1 Kinase (PIM1) [ 572 ]
 Corticotropin releasing factor receptor [ 135 ] PIM-3 Kinase [ 2 ]
 Cyclic AMP-dependent protein kinase (PKA) [ 10 ] PKC alpha and beta-2 [ 133 ]
 Cyclin-Dependent Kinase 1 (CDK1) [ 980 ] Plasmepsin I [ 93 ]
 Cyclin-Dependent Kinase 2 (CDK2) [ 1870 ] Plasmepsin II [ 107 ]
 Cyclin-Dependent Kinase 2 (CDK2) Mutant (F82H) [ 1 ] Plasmepsin IV [ 11 ]
 Cyclin-Dependent Kinase 2 (CDK2) Mutant (F82H/L83V/H84D) [ 2 ] Plasmin [ 54 ]
 Cyclin-Dependent Kinase 2 (CDK2) Mutant (F82H/L83V/H84D/K89T) [ 2 ] Plasminogen [ 100 ]
 Cyclin-Dependent Kinase 2 (CDK2) Mutant (K89T) [ 2 ] Plasminogen activator inhibitor-1 [ 13 ]
 Cyclin-Dependent Kinase 2 (CDK2) Mutant (L83V/H84D) [ 1 ] Platelet-derived growth factor receptor [ 60 ]
 Cyclin-Dependent Kinase 4 (CDK4) [ 1043 ] Polo-Like Kinase 1 [ 1 ]
 Cyclin-dependent kinase 4/cyclin D2 [ 508 ] Polo-Like Kinase 3 [ 31 ]
 Cyclin-Dependent Kinase 5 (CDK5) [ 309 ] Polo-Like Kinase 4 [ 21 ]
 Cyclin-dependent kinase 5 regulatory subunit 1 [ 53 ] Poly (ADP-ribose) Polymerase-2 (PARP-2) [ 36 ]
 Cyclin-Dependent Kinase 6 (CDK6) [ 8 ] Poly [ADP-ribose] polymerase 1 (PARP) [ 243 ]
 Cyclin-Dependent Kinase 7 (CDK7) [ 29 ] Porphobilinogen synthase [ 20 ]
 Cyclin-Dependent Kinase 9 (CDK9) [ 13 ] PPIase Pin1 [ 15 ]
 Cyclin-dependent protein kinase 2 variant (CDK2 A144C) [ 1 ] Pregnane X Receptor [ 12 ]
 Cyclin-dependent protein kinase 2 variant (CDK2 C118L) [ 1 ] PRKD3 [ 7 ]
 Cyclin-dependent protein kinase 2 variant (CDK2 C118L/A144C) [ 1 ] Probable low molecular weight protein-tyrosine-phosphatase [ 1 ]
 Cyclooxygenase [ 69 ] Progesterone Receptor (PR) [ 78 ]
 Cyclooxygenase-1 (COX-1) [ 71 ] Prokineticin Receptor 1 (PKR1) [ 3 ]
 Cyclooxygenase-2 [ 6 ] Prokineticin Receptor 2 (PKR2) [ 3 ]
 Cyclophilin A [ 16 ] Prolylcarboxypeptidase (PRCP) [ 10 ]
 Cytochrome P450 11B2 [ 110 ] Prostaglandin D Synthase [ 16 ]
 Cytochrome P450 17A1 [ 109 ] Prostaglandin E2 receptor [ 9 ]
 Cytochrome P450 1A2 [ 1 ] Prostanoid EP1 Receptor [ 19 ]
 Cytochrome P450 1B1 [ 5 ] Prostanoid EP2 Receptor [ 19 ]
 Cytochrome P450 2A13 (CYP2A13) [ 33 ] Prostanoid EP3 Receptor [ 19 ]
 Cytochrome P450 2A6 [ 64 ] Prostanoid EP4 Receptor [ 19 ]
 Cytochrome P450 2C19 [ 8 ] Prostanoid IP receptor [ 17 ]
 Cytochrome P450 2C9 [ 29 ] Protease [ 77 ]
 Cytochrome P450 2D6 [ 8 ] Protein Disulfide-Isomerase (PDI) [ 16 ]
 Cytochrome P450 2E1 [ 9 ] Protein farnesyltransferase [ 90 ]
 Cytochrome P450 3A [ 91 ] Protein Farnesyltransferase (PFT) [ 154 ]
 Cytochrome P450 3A1 [ 11 ] Protein kinase B (Akt 1) [ 272 ]
 Cytochrome P450 51(CYP51) [ 26 ] Protein kinase B (Akt 2) [ 57 ]
 Cytochrome P450 51(CYP51) Mutant (F78L) [ 2 ] Protein Kinase C [ 167 ]
 Cytosol aminopeptidase [ 19 ] Protein kinase C (PKC) [ 44 ]
 D-Amino Acid Oxidase (DAAO) [ 68 ] Protein kinase C alpha [ 13 ]
 D-Aspartate Oxidase (DDO) [ 23 ] Protein Kinase C, alpha [ 147 ]
 D-lactate dehydrogenase [ 4 ] Protein Kinase C, beta I [ 10 ]
 dCTP pyrophosphatase 1 (DCTPP1) [ 5 ] Protein kinase C, delta [ 118 ]
 Dehydropeptidase-I (DHP-1) [ 13 ] Protein kinase C, epsilon [ 100 ]
 Delta Opioid Receptor [ 147 ] Protein kinase C, eta [ 55 ]
 delta/kappa opioid receptor [ 3 ] Protein kinase C, gamma [ 45 ]
 Dengue Virus 1 (DENV1) NS2B-NS3 Protease [ 10 ] Protein Kinase C, theta [ 93 ]
 Dengue Virus 2 (DENV2) NS2B-NS3 Protease [ 15 ] Protein Kinase D1 [ 38 ]
 Dengue Virus 3 (DENV3) NS2B-NS3 Protease [ 10 ] Protein Kinase YpkA [ 4 ]
 Dengue Virus 4 (DENV4) NS2B-NS3 Protease [ 10 ] Protein Tyrosine Phosphatase CD45 [ 1 ]
 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) [ 22 ] Protein Tyrosine Phosphatase LAR [ 1 ]
 Diacyl Glycerolacyltransferase 1 (DGAT-1) [ 2 ] Protein Tyrosine Phosphatase PTPB [ 5 ]
 Diacyl Glycerolacyltransferase 2 (DGAT-2) [ 2 ] Protein Wnt [ 4 ]
 Diacylglycerol O-acyltransferase 1 [ 32 ] Protein-glutamine gamma-glutamyltransferase 2 (TG2) [ 18 ]
 Dihydrodipicolinate reductase (DHPR) [ 4 ] Protein-tyrosine phosphatase 1B [ 52 ]
 Dihydrofolate reductase [ 176 ] Protein-Tyrosine Phosphatase 1B (PTP1B) [ 266 ]
 Dihydrofolate Reductase (DHFR) [ 452 ] Protein-Tyrosine Phosphatase 1B (PTP1B) Mutant (G117E) [ 1 ]
 Dihydrofolate Reductase (DHFR) Mutant (F98Y) [ 2 ] Protein-Tyrosine Phosphatase 1B (PTP1B) Mutant (L119V) [ 2 ]
 Dihydrofolate Reductase (DHFR) Mutant (I100L) [ 2 ] Protein-Tyrosine Phosphatase 1B (PTP1B) Mutant (M114V) [ 1 ]
 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) [ 22 ] Protein-Tyrosine Phosphatase 1B (PTP1B) Mutant (V113I) [ 1 ]
 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant KICB1 [ 3 ] Protein-Tyrosine Phosphatase 1B (PTP1B) Mutant (V113L/M114V) [ 1 ]
 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant SP21 [ 19 ] Protein-tyrosine phosphatase 1C [ 1 ]
 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant V1/S [ 3 ] Protein-Tyrosine Phosphatase SHP-1 [ 22 ]
 Dihydroorotase (DHO) [ 3 ] Protein-Tyrosine Phosphatase SHP-2 [ 51 ]
 Dihydroorotate dehydrogenase [ 131 ] Proto-oncogene tyrosine-protein kinase (Src) [ 900 ]
 Dihydroorotate Dehydrogenase (DHODH) [ 197 ] Proto-oncogene tyrosine-protein kinase receptor Ret [ 14 ]
 Dihydroorotate Dehydrogenase (DHODH) Mutant (H185A) [ 13 ] Pteridine Reductase 1 (PTR1) [ 11 ]
 Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A) [ 13 ] Purine nucleoside phosphorylase [ 6 ]
 Dipeptidyl peptidase 4 (DDP4) [ 850 ] Purine Nucleoside Phosphorylase (PNP) [ 12 ]
 Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) [ 46 ] Putative farnesyl pyrophosphate synthase [ 3 ]
 Dipeptidyl peptidase III [ 12 ] Quinone reductase 1) [ 58 ]
 Dipeptidyl peptidase IV [ 27 ] Quinone Reductase 2 (QR2) [ 27 ]
 Dipeptidyl peptidase IX [ 275 ] RAF-1 [ 1 ]
 Dipeptidyl Peptidase VII (DPP-VII) (QPP) [ 381 ] Receptor tyrosine-protein kinase erbB-4 (HER4) [ 4 ]
 Dipeptidyl peptidase VIII [ 400 ] Receptor-interacting serine/threonine-protein kinase 1 [ 2 ]
 Disulfide bond formation protein B (DsbB) [ 8 ] Receptor-type tyrosine-protein kinase FLT3 [ 64 ]
 DNA Gyrase [ 49 ] Receptor-type tyrosine-protein phosphatase F (LAR) [ 1 ]
 DNA Ligase (MtuLigA) [ 7 ] Renin [ 232 ]
 DNA Ligase I [ 4 ] Retinoic Acid Receptor, alpha [ 12 ]
 DNA Polymerase alpha [ 12 ] Retinoic Acid Receptor, beta [ 10 ]
 DNA Polymerase beta [ 10 ] Retinoic Acid Receptor, gamma [ 11 ]
 DNA polymerase gamma subunit 1 [ 2 ] Retinoic Acid Receptors Gamma / Alpha [ 2 ]
 DNA polymerase III subunit gamma [ 13 ] Retinoid X receptor alpha (F313I/L436F) [ 1 ]
 DNA polymerase IIIC [ 2 ] Retinoid X receptor alpha (F313I/L436V) [ 1 ]
 DNA polymerase IIIE [ 4 ] Reverse transcriptase [ 5 ]
 DNA topoisomerase II [ 6 ] Rho Kinase 1 [ 6 ]
 DNA Topoisomerase IV [ 27 ] Rho Kinase 2 [ 352 ]
 Dopamine D2 receptor [ 58 ] Rho-associated protein kinase [ 69 ]
 Dopamine D2 receptor and serotonin 1a receptor [ 469 ] Rho-kinase (ROCK I) [ 2 ]
 Dopamine D2 receptor and serotonin 2a receptor [ 50 ] Rho-kinase (ROCK II) [ 12 ]
 Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) [ 33 ] Rhomboid protease (AaROM) [ 2 ]
 Dopamine receptor [ 47 ] Rhomboid protease (AfROM) [ 2 ]
 Dopamine Transporter (DAT) [ 83 ] Rhomboid protease (BsYqgP) [ 2 ]
 Dual specificity protein kinase CLK4 [ 13 ] Rhomboid protease (EcGlpG) [ 2 ]
 Dual specificity protein kinase TTK [ 2 ] Rhomboid protease (HiGlpG) [ 3 ]
 Dual specificity protein phosphatase (MKPX) [ 1 ] Rhomboid protease (MmRHBDL1) [ 2 ]
 Dual Specificity Protein Phosphatase 1 [ 165 ] Rhomboid protease (MmRHBDL3) [ 2 ]
 Dual specificity protein phosphatase 3 [ 19 ] Rhomboid protease (PhROM) [ 2 ]
 Dual specificty protein kinase CLK1 [ 3 ] Rhomboid protease (PsAarA) [ 2 ]
 Dual-specificity tyrosine-phosphorylation regulated kinase 1A [ 3 ] Rhomboid protease (TmROM) [ 4 ]
 dUTP pyrophosphatase [ 11 ] Rhomboid protease (VcROM) [ 2 ]
 E3 ubiquitin-protein ligase (UHRF1) [ 25 ] Ribonuclease H [ 2 ]
 EGF-R Tyrosine Kinase [ 4 ] Ribonuclease H1 [ 8 ]
 EGF-R Tyrosine Kinase Mutant (G719C) [ 20 ] Ribosomal protein S6 kinase alpha 1 [ 8 ]
 EGF-R Tyrosine Kinase Mutant (G719S) [ 2 ] Ribosomal protein S6 kinase alpha 2 [ 1 ]
 EGF-R Tyrosine Kinase Mutant (L858R) [ 14 ] Ribosomal protein S6 kinase alpha 4 [ 4 ]
 EGF-R Tyrosine Kinase Mutant (L858R/T790M) [ 2 ] Ribosomal protein S6 kinase alpha 5 [ 15 ]
 EGF-R Tyrosine Kinase Mutant (T790M) [ 6 ] Ribosomal protein S6 kinase alpha 6 [ 1 ]
 Endothelin-Converting Enzyme 1 [ 29 ] Ribosomal S6 Kinase 1 (RSK-1) [ 1 ]
 Enoyl-ACP reductase (ENR) [ 21 ] Ribosomal S6 Kinase 2 (RSK-2) [ 1 ]
 Enoyl-ACP Reductase (FabI) [ 181 ] Runt-Related Transcription Factor 1 Isoform AML1C [ 233 ]
 Enoyl-ACP Reductase (FabK) [ 5 ] RXR alpha/PPAR gamma [ 93 ]
 Enoyl-ACP Reductase (InhA) [ 113 ] S-adenosylmethionine decarboxylase 1 [ 34 ]
 Enoyl-ACP Reductase (PfENR) [ 28 ] S-Adenosylmethionine Synthase (AdoMet) [ 6 ]
 Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl) [ 20 ] Sarco/endoplasmic Reticulum Ca2+ ATPase 1 [ 31 ]
 EPHA4 [ 5 ] SARS Coronavirus 3C-like Protease [ 86 ]
 Ephrin type-A receptor 3 (EPHA3) [ 1 ] SARS Coronavirus Coronavirus Papain-Like Protease [ 24 ]
 Epidermal growth factor receptor [ 1134 ] Sentrin-specific protease 1 (SENP1) [ 28 ]
 Epidermal growth factor receptor (EGFR) [ 25 ] Sentrin-specific protease 2 (SENP2) [ 28 ]
 Epidermal growth factor receptor and ErbB2 (HER1 and HER2) [ 4 ] Sentrin-specific protease 7 (SENP7) [ 8 ]
 Epoxide Hydrolase B (EHB) [ 20 ] Serine/threonine-protein kinase 10 [ 2 ]
 Equilibrative Nucleoside Transporter 1 (ENT1) [ 80 ] Serine/threonine-protein kinase 2 (CaPkh2) [ 4 ]
 ErbB-2 (HER2) Tyrosine Kinase [ 144 ] Serine/threonine-protein kinase AKT [ 179 ]
 ErbB-4 (HER4) Tyrosine Kinase [ 9 ] Serine/threonine-protein kinase ATR [ 4 ]
 ERK-2 [ 9 ] Serine/threonine-protein kinase Aurora-A [ 334 ]
 Estradiol 17-beta-dehydrogenase 2 [ 16 ] Serine/threonine-protein kinase Aurora-B [ 90 ]
 Estrogen receptor [ 265 ] Serine/threonine-protein kinase Aurora-C [ 1 ]
 Estrogen Receptor (ER-alpha) [ 85 ] Serine/threonine-protein kinase B-raf [ 72 ]
 Estrogen Receptor (ER-beta) [ 70 ] Serine/threonine-protein kinase Chk1  [ 5 ]
 Estrogen-Related Receptor, alpha [ 2 ] Serine/threonine-protein kinase D2 (PKD2) [ 7 ]
 Estrogen-Related Receptor, gamma [ 31 ] Serine/threonine-protein kinase MRCK alpha [ 5 ]
 F-box and leucine-rich repeat protein 11 (FBXL11) [ 6 ] Serine/threonine-protein kinase MRCK beta [ 5 ]
 Factor VIIa (fVIIa) [ 46 ] Serine/threonine-protein kinase MST2 [ 1 ]
 Factor Xa (fXa) [ 57 ] Serine/threonine-protein kinase PAK 4 [ 4 ]
 Factor XIIa (fXIIa) [ 123 ] Serine/threonine-protein kinase PAK6 [ 3 ]
 Falcipain-2 [ 30 ] Serine/threonine-protein kinase PAK7 [ 1 ]
 Farnesoid X-Activated Receptor [ 21 ] Serine/threonine-protein kinase PIM-3 [ 68 ]
 Farnesyl diphosphate synthase [ 23 ] Serine/threonine-protein kinase PIM2 [ 464 ]
 Fas-associated protein-tyrosine phosphatase 1 (PTP-BAS) [ 1 ] Serine/threonine-protein kinase PIM3 [ 193 ]
 Fatty Acid Amide Hydrolase [ 165 ] Serine/threonine-protein kinase PLK1 [ 187 ]
 Fatty Acid Synthase [ 46 ] Serine/threonine-protein kinase PLK2 [ 32 ]
 Fibroblast Activation Protein (FAP) [ 18 ] Serine/threonine-protein kinase PLK3 [ 18 ]
 Fibroblast growth factor receptor 1 [ 562 ] Serine/threonine-protein kinase RAF and Dual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK) [ 70 ]
 Fibroblast growth factor receptor 2 [ 10 ] Serine/threonine-protein kinase/endoribonuclease IRE1 Alpha [ 302 ]
 Fibroblast growth factor receptor 3 [ 17 ] Serotonin (5-HT) receptor [ 288 ]
 fMet-Leu-Phe receptor 1/2 [ 18 ] Serotonin 1 (5-HT1) receptor [ 34 ]
 Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 [ 90 ] Serotonin 3 (5-HT3) receptor [ 62 ]
 FtsZ [ 20 ] Serotonin N-acetyltransferase (AANAT) [ 15 ]
 G protein-coupled receptor 44 [ 132 ] Serotonin receptor (2b and 2c) [ 10 ]
 G-protein coupled bile acid receptor 1 [ 9 ] Serotonin Receptor 4 [ 7 ]
 G-protein coupled receptor 4 (GPR4) [ 37 ] Serotonin Receptor 7 [ 34 ]
 G-protein Coupled Receptor 54 [ 12 ] Serotonin Transporter (SERT) [ 59 ]
 GABAA Receptor Mutant, alpha-1 (A160C), beta-2, gamma-2 [ 3 ] Serotonin transporters (SERT) [ 32 ]
 GABAA Receptor Mutant, alpha-1 (D97C), beta-2, gamma-2 [ 1 ] Serum paraoxonase 1 (PON1) [ 6 ]
 GABAA Receptor Mutant, alpha-1 (F99C), beta-2, gamma-2 [ 3 ] SF3B3 [ 12 ]
 GABAA Receptor Mutant, alpha-1 (G157C), beta-2, gamma-2 [ 3 ] Siderocalin (Scn) [ 4 ]
 GABAA Receptor Mutant, alpha-1 (G200C), beta-2, gamma-2 [ 3 ] Sigma-1 receptor [ 9 ]
 GABAA Receptor Mutant, alpha-1 (S204C), beta-2, gamma-2 [ 3 ] Sodium-Dependent Glucose Cotransporter 1 (SGLT1) [ 5 ]
 GABAA Receptor Mutant, alpha-1 (S205C), beta-2, gamma-2 [ 3 ] Sodium-Dependent Glucose Cotransporter 2 (SGLT2) [ 5 ]
 GABAA Receptor Mutant, alpha-1 (T162C), beta-2, gamma-2 [ 3 ] Sortase A (SrtA) [ 113 ]
 GABAA Receptor Mutant, alpha-1 (T206C), beta-2, gamma-2 [ 3 ] Sphingosine 1-phosphate receptor 1 (S1P1) [ 57 ]
 GABAA Receptor Mutant, alpha-1 (V202C), beta-2, gamma-2 [ 3 ] Sphingosine 1-Phosphate Receptor 2 [ 4 ]
 GABAA Receptor Mutant, alpha-1 (V211C), beta-2, gamma-2 [ 3 ] Sphingosine 1-Phosphate Receptor 3 [ 32 ]
 GABAA Receptor Mutant, alpha-1 (Y209C), beta-2, gamma-2 [ 1 ] Sphingosine 1-Phosphate Receptor 4 [ 23 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (A79C) [ 3 ] Sphingosine 1-Phosphate Receptor 5 [ 31 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (Chimera) [ 3 ] Src [ 108 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (D56C) [ 3 ] Src Mutant (S345C) [ 4 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (F77C) [ 1 ] Src Mutant (S345C/T338M) [ 4 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (L140C) [ 3 ] Src Mutant (T338M) [ 9 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (M130C) [ 3 ] Steroid 11-beta-Hydroxylase (CYP11B1) [ 101 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (R132C) [ 3 ] Steroid 5-alpha-reductase [ 5 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (R144C) [ 3 ] Steroid Sulfatase (STS) [ 45 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (R185C) [ 3 ] Steroidogenic Factor 1 [ 23 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (R194C) [ 3 ] Sterol 14-alpha demethylase (CYP51) [ 34 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (T126C) [ 3 ] Stromelysin-1 [ 128 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (T142C) [ 3 ] SUMO-1-specific protease [ 8 ]
 GABAA Receptor Mutant, alpha-1, beta-2, gamma-2 (T81C) [ 3 ] T-cell protein-tyrosine phosphatase [ 1 ]
 GABAA Receptor, alpha-1, beta-2, gamma-2 [ 3 ] T-Cell Protein-Tyrosine Phosphatase (TCPTP) [ 56 ]
 GABAA Receptor, alpha-1, beta-3, gamma-2 [ 8 ] T-Cell Protein-Tyrosine Phosphatase (TCPTP) Mutant (V121L) [ 2 ]
 GABAA Receptor, alpha-2, beta-2, gamma-2 [ 3 ] Tankyrase-1 (TNKS1) [ 1 ]
 GABAA Receptor, alpha-2, beta-3, gamma-2 [ 8 ] TGF-beta receptor type-1 [ 43 ]
 GABAA Receptor, alpha-3, beta-2, gamma-2 [ 3 ] Thrombin [ 150 ]
 GABAA Receptor, alpha-3, beta-3, gamma-2 [ 7 ] Thrombin and coagulation factor VII [ 1473 ]
 GABAA Receptor, alpha-4, beta-2, gamma-2 [ 3 ] Thrombin and urokinase-type plasminogen activator [ 7 ]
 GABAA Receptor, alpha-4, beta-3, gamma-2 [ 4 ] Thromboxane A2 Synthase (P450 TxA2) [ 20 ]
 GABAA Receptor, alpha-5, beta-2, gamma-2 [ 3 ] Thymidine kinase [ 58 ]
 GABAA Receptor, alpha-5, beta-3, gamma-2 [ 8 ] Thymidine Phosphorylase (TP) [ 74 ]
 GABAA Receptor, alpha-6, beta-2, gamma-2 [ 3 ] Thymidylate synthase [ 97 ]
 GABAA Receptor, alpha-6, beta-3, gamma-2 [ 7 ] Thymidylate synthase (TS) [ 7 ]
 Gag polyprotein [ 10 ] Thyroid hormone receptor [ 111 ]
 Galectin-1 [ 14 ] Thyroid Hormone Receptor (TR-alpha) [ 54 ]
 Galectin-3 [ 23 ] Thyroid Hormone Receptor (TR-beta) [ 160 ]
 Galectin-7 [ 12 ] Tie-2 [ 222 ]
 Galectin-8 [ 11 ] Tissue-type plasminogen activator [ 94 ]
 Galectin-9 [ 12 ] TNF-alpha-Converting Enzyme [ 86 ]
 gamma-Aminobutyric Acid Type B Receptor [ 16 ] Trans-sialidase [ 6 ]
 GAR Tfase [ 18 ] Transcription Factor STAT1 [ 11 ]
 Gastric Inhibitory Polypeptide Receptor (GIPR) [ 30 ] Transcription Factor STAT1:STAT3 Dimer [ 2 ]
 General receptor of phosphoinositides 1 (GRP1) [ 2 ] Transcription Factor STAT3 [ 96 ]
 Geranylgeranyl Diphosphate Synthase (GGPPS) [ 61 ] Transporter [ 19 ]
 Geranylgeranyl Transferase (GGTase-I) [ 59 ] Triacylglycerol Hydrolase [ 46 ]
 Geranylgeranyl transferase type I [ 43 ] TRKA [ 150 ]
 Ghrelin receptor [ 131 ] tRNA synthetase (AspRS) [ 3 ]
 Glucagon [ 99 ] tRNA synthetase (GlnRS) [ 2 ]
 Glucagon Receptor [ 30 ] tRNA synthetase (GluRS) [ 6 ]
 Glucagon Receptor (GCGR) [ 138 ] tRNA synthetase (GlyRS) [ 6 ]
 Glucan Synthase [ 14 ] tRNA synthetase (IleRS) [ 21 ]
 Glucocerebrosidase (Acid beta-Glucosidase) [ 150 ] tRNA synthetase (PheRS) [ 53 ]
 Glucocorticoid Receptor (GR) [ 133 ] tRNA synthetase (TyrRS) [ 4 ]
 Glucosamine-6- Phosphate Synthase [ 15 ] tRNA-guanine transglycosylase (TGT) [ 10 ]
 Glutamate Carboxypeptidase II (GCPII) [ 42 ] Trypanothione reductase [ 19 ]
 Glutamine synthetase [ 6 ] Trypanothione Reductase (TR) [ 11 ]
 Glutaminyl Cyclase [ 98 ] Trypanothione Reductase (TryR) [ 19 ]
 Glutathione S-transferase E2 [ 5 ] Trypanothione synthetase (TryS) [ 4 ]
 Glycogen Phosphorylase (PYGL) [ 105 ] Trypsin [ 443 ]
 Glycogen Phosphorylase (PYGM) [ 47 ] Tryptase [ 53 ]
 Glycogen phosphorylase, muscle form [ 26 ] Tryptophanase [ 4 ]
 Glycogen Synthase Kinase-3, alpha [ 173 ] Tubulin--tyrosine ligase [ 6 ]
 Glycogen Synthase Kinase-3, beta [ 676 ] Tyrosinase [ 33 ]
 Glycosylasparaginase (GA) [ 10 ] Tyrosine Kinase ACK1 [ 10 ]
 Golgi alpha-mannosidase II [ 35 ] Tyrosine Kinase c-Kit Mutant (N822K) [ 7 ]
 Grb2-SH2 [ 15 ] Tyrosine Kinase c-Kit Mutant (V559D) [ 7 ]
 Grp78 [ 14 ] Tyrosine Kinase c-Kit Mutant (V559D/T670I) [ 7 ]
 Haspin (465-798) [ 1 ] Tyrosine Kinase c-Met [ 1 ]
 HCV NS3 Helicase [ 12 ] Tyrosine Kinase c-Met Mutant (D1228H) [ 1 ]
 HCV NS3 Proteinase [ 2 ] Tyrosine Kinase c-Met Mutant (H1094R) [ 1 ]
 HCV NS3-NS4A Serine Proteinase [ 346 ] Tyrosine Kinase c-Met Mutant (M1250T) [ 1 ]
 HCV NS5B Polymerase [ 183 ] Tyrosine Kinase c-Met Mutant (V1092I) [ 1 ]
 HCV NS5B Polymerase Mutant (M414T) [ 2 ] Tyrosine Kinase c-Met Mutant (Y1230H) [ 1 ]
 HCV NS5B Polymerase Mutant (M423K) [ 2 ] Tyrosine Kinase c-Ret [ 15 ]
 HCV NS5B Polymerase Mutant (P495A) [ 2 ] Tyrosine Kinase DDR1 [ 24 ]
 HCV NS5B Polymerase Mutant (R501E) [ 2 ] Tyrosine Kinase DDR2 [ 13 ]
 Heat Shock 70kDa Protein 1 [ 76 ] Tyrosine Kinase EPHA3 [ 15 ]
 Heat Shock Protein 90 (Hsp90) [ 14 ] Tyrosine Kinase EPHA6 [ 16 ]
 Heat shock protein HSP90 [ 466 ] Tyrosine Kinase EPHA7 [ 10 ]
 Hematopoietic protein-tyrosine phosphatase (HEPTP) [ 1 ] Tyrosine Kinase EPHB3 [ 3 ]
 Heme Oxygenase 1 (HO-1) [ 101 ] Tyrosine Kinase EphB4 [ 30 ]
 Heme Oxygenase 2 (HO-2) [ 103 ] Tyrosine Kinase FAK [ 2 ]
 Hepsin [ 6 ] Tyrosine Kinase FLT3 Mutant (D835H) [ 23 ]
 Hexokinase [ 7 ] Tyrosine Kinase FLT3 Mutant (D835Y) [ 21 ]
 Hexokinase type IV [ 34 ] Tyrosine Kinase FLT3 Mutant (N841I) [ 22 ]
 Histamine H1 Receptor [ 1 ] Tyrosine Kinase TrkA [ 4 ]
 Histamine H2 Receptor [ 5 ] Tyrosine Kinase ZAP-70 [ 30 ]
 Histamine H3 receptor [ 30 ] Tyrosine-protein kinase ABL (E255V) [ 1 ]
 Histamine H4 Receptor [ 21 ] Tyrosine-protein kinase ABL (Y253H) [ 1 ]
 Histamine receptor (H3) [ 74 ] Tyrosine-protein kinase ABL1 [ 10 ]
 Histamine receptor (H4) [ 98 ] Tyrosine-protein kinase BRK [ 1 ]
 Histone deacetylase [ 79 ] Tyrosine-protein kinase BTK [ 133 ]
 Histone Deacetylase (pfHDAC-1) [ 23 ] Tyrosine-protein kinase CSK [ 5 ]
 Histone deacetylase 1 (HDAC1) [ 203 ] Tyrosine-protein kinase ITK [ 79 ]
 Histone Deacetylase 10 (HDAC10) [ 18 ] Tyrosine-protein kinase JAK1 [ 3 ]
 Histone Deacetylase 2 (HDAC2) [ 43 ] Tyrosine-protein kinase JAK2 [ 215 ]
 Histone deacetylase 3 [ 88 ] Tyrosine-protein kinase JAK3 [ 163 ]
 Histone deacetylase 4 (HDAC4) [ 78 ] Tyrosine-protein kinase Met [ 132 ]
 Histone Deacetylase 4 (HDAC4) Mutant (H976Y) [ 48 ] Tyrosine-protein kinase receptor FLT4 [ 22 ]
 Histone Deacetylase 5 (HDAC5) [ 8 ] Tyrosine-protein kinase SRC (E280V) [ 1 ]
 Histone deacetylase 6 (HDAC6) [ 365 ] Tyrosine-protein kinase SRC (F278H) [ 1 ]
 Histone deacetylase 8 [ 52 ] Tyrosine-protein kinase SYK [ 476 ]
 Histone deacetylase 9 (HDAC9) [ 2 ] Tyrosine-protein kinase V-ABL [ 30 ]
 Histone Lysine Demethylase [ 24 ] Tyrosine-protein kinase ZAP-70  [ 50 ]
 Histone-Arginine Methyltransferase CARM1 [ 19 ] Tyrosine-Specific Protein Kinase [ 6 ]
 Histone-lysine N-methyltransferase EZH2 [ 5 ] Ubiquitin C-terminal Hydrolase L3 (UCH-L3) [ 10 ]
 HIV-1 Integrase [ 101 ] Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) [ 74 ]
 HIV-1 Protease [ 2432 ] Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) [ 24 ]
 HIV-1 Protease AE [ 7 ] UDP-3-O-Acyl-GlcNAc Deacetylase (LpxC) [ 69 ]
 HIV-1 Protease AE Mutant (V82F) [ 7 ] Uracil-DNA glycosylase (UNG) [ 6 ]
 HIV-1 Protease AE-P [ 7 ] Urea Amidohydrolase [ 22 ]
 HIV-1 Protease AE-P Mutant (F82V) [ 7 ] Urease [ 10 ]
 HIV-1 Protease B Subtype [ 7 ] Urokinase (uPA) [ 285 ]
 HIV-1 Protease B Subtype Mutant (V82F) [ 7 ] Urokinase (uPA) Mutant (S190A) [ 14 ]
 HIV-1 Protease Mutant (A71V) [ 5 ] Urokinase-type plasminogen activator (uPA) [ 7 ]
 HIV-1 Protease Mutant (A71V/V82T/I84V) [ 1 ] Vanilloid receptor [ 401 ]
 HIV-1 Protease Mutant (D30N) [ 7 ] Vascular adhesion protein 1 (VAP-1) [ 19 ]
 HIV-1 Protease Mutant (D30N/A71V) [ 5 ] Vascular endothelial growth factor receptor 2 [ 1102 ]
 HIV-1 Protease Mutant (D30N/M36I) [ 5 ] Vasopressin receptor [ 60 ]
 HIV-1 Protease Mutant (D30N/M36I/A71V) [ 5 ] Vasopressin V1 receptor [ 45 ]
 HIV-1 Protease Mutant (G73S) [ 3 ] Vasopressin V2 Receptor [ 2 ]
 HIV-1 Protease Mutant (I47L) [ 1 ] VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta) [ 585 ]
 HIV-1 Protease Mutant (I50L) [ 1 ] VEGFR-1 (Flt-1) [ 241 ]
 HIV-1 Protease Mutant (I50V) [ 11 ] VEGFR-2 (KDR) [ 81 ]
 HIV-1 Protease Mutant (I84V) [ 3 ] VEGFR-3 (FLT4) [ 1 ]
 HIV-1 Protease Mutant (L10I,L19Q,K20R,E35D,M36I, ..) [ 6 ] Viral IAP-associated factor 1 (VIAF) [ 7 ]
 HIV-1 Protease Mutant (L23I) [ 1 ] Vitamin D receptor [ 6 ]
 HIV-1 Protease Mutant (L23V) [ 1 ] Vitamin D-binding protein [ 7 ]
 HIV-1 Protease Mutant (L24I) [ 3 ] Vitamin K-dependent protein C [ 1 ]
 HIV-1 Protease Mutant (L76M) [ 1 ] Voltage-gated potassium channel [ 84 ]
 HIV-1 Protease Mutant (L90M) [ 2 ] West Nile Virus (WNV) NS2B-NS3 Protease [ 38 ]
 HIV-1 Protease Mutant (M36I) [ 5 ] X-linked inhibitor of apoptosis protein (XIAP) [ 40 ]
 HIV-1 Protease Mutant (M36I/A71V) [ 5 ] Xanthine oxidase [ 11 ]
 HIV-1 Protease Mutant (M46I,L63P,A71V,V82F,I84V) [ 6 ] XIAP-BIR3 [ 191 ]
 HIV-1 Protease Mutant (V32I) [ 1 ]